张东生

专业特长：肿瘤内科治疗（化学治疗、靶向治疗）的临床工作及抗癌药物研究。擅长消化道肿瘤（包括食道癌、胃癌、肠癌、胰腺癌、肝胆癌）软组织肿瘤及头颈部肿瘤的内科治疗及研究。

学习及工作经历：
　　1991年—1996年：皖南医学院就读，医疗系，本科
　　1996年—2000年；皖南医学院弋矶山医院工作
　　2000年—2003年：中山医科大学就读，肿瘤学硕士研究生
　　2003年—至今：中山大学肿瘤医院工作；期间获得肿瘤学博士研究生学位

1. Zhang DS, Wang DS, Wang ZQ, Wang FH, Luo HY, Qiu MZ, Wang F, Li YH, Xu RH. Phase I/II study of albumin-bound nab-paclitaxel plus gemcitabine administered to Chinese patients with advanced pancreatic cancer. Cancer Chemother Pharmacol. 2013 Apr;71(4):1065-72. doi: 　　10.1007/s00280-013-2102-4. Epub 2013 Mar 13.

　　2. Li S, Zhang DS (co-first author), Sun J, Li Z, Deng L, Zou B, Zhan J, Jiang W Pharmacokinetics and tolerability of human mouse chimeric anti-CD22 monoclonal antibody in Chinese patients with CD22-positive non-Hodgkin lymphoma.MAbs. 2012 Mar 1;4(2). [Epub ahead of print]

　　3. Qiu MZ, Zhang DS (co-first author), Ruan DY, Luo HY, Wang ZQ, Zhou ZW, Wang FH, Li YH, Xu RH. A relationship between ABO blood groups and clinicopathologic characteristics of patients with gastric adenocarcinoma in China.Med Oncol. 2011 Dec;28 Suppl 1:S268-73. doi: 10.1007/s12032-010-9735-5. Epub 2010 Nov 4.

　　4. Liu TZ, Zhang DS, Liang Y, Zhou NN, Gao HF, Liu KJ, Wu HY Treatment strategies and prognostic factors of patients with primary germ cell tumors in the mediastinum. J Cancer Res Clin Oncol. 2011 Nov;137(11):1607-12. doi: 10.1007/s00432-011-1028-7. Epub 2011 Aug 18.

　　5. Wang DS, Zhang DS, Qiu MZ, Wang ZQ, Luo HY, Wang FH, Li YH, Xu RH. Prognostic factors and survival in patients with neuroendocrine tumors of the pancreas. Tumour Biol. 2011 Aug;32(4):697-705. doi: 10.1007/s13277-011-0170-9. Epub 2011 Apr 9.

　　6. Qiu MZ, Wang ZQ, Zhang DS, Luo HY, Zhou ZW, Wang FH, Li YH, Jiang WQ, Xu RH. Clinicopathological characteristics and prognostic analysis of gastric cancer in the young adult in China. Tumour Biol. 2011 Jun;32(3):509-14. doi: 10.1007/s13277-010-0145-2. Epub 2010 Dec 23.

　　7. Qiu MZ, Wang ZQ, Zhang DS, Liu Q, Luo HY, Zhou ZW, Li YH, Jiang WQ, Xu RH. Comparison of 6th and 7th AJCC TNM staging classification for carcinoma of the stomach in China. Ann Surg Oncol. 2011 Jul;18(7):1869-76. doi: 10.1245/s10434-010-1542-x. Epub 2011 Jan 19.

　　8. Qiu MZ, Cai MY, Zhang DS, Wang ZQ, Wang DS, Li YH, Xu RH. Clinicopathological characteristics and prognostic analysis of Lauren classification in gastric adenocarcinoma in China.J Transl Med. 2013 Mar 6;11:58. doi: 10.1186/1479-5876-11-58.

　　9. Wang F, Xu RH, Luo HY, Zhang DS, Jiang WQ, Huang HQ, Sun XF, Xia ZJ, Guan ZZ. Clinical and prognostic analysis of hepatitis B virus infection in diffuse large B-cell lymphoma. BMC Cancer. 2008 Apr 23;8:115. doi: 10.1186/1471-2407-8-115.

　　10. ZHANG Dong-sheng; JIANG Wen-qi; LI Su; et al. Expression of Glycoprotein 90K in Non-Hodgkin s Lymphoma and Its Clinical  Significance .Chinese Journal of Cancer 2005;08.

　　11. ZHANG Dong-sheng; JIANG Wen-qi; LI Su; et al. Detection of serun 90K/Mac-2BP in non-Hodgkin s lymphoma and its clinical significance.Chian Oconlogy,2006；6.

1. 广东省抗癌协会会员

　　2. 中国抗癌协会大肠癌专业委员会员

　　3. 广东省抗癌协会大肠癌专业委员会青年委员会委员

　　4. 广东省抗癌协会化疗专业委员会员

　　5. 中国医师协会会员

擅长胃肠道肿瘤、恶性淋巴瘤、头颈癌（包括鼻咽癌）、软组织肉瘤等恶性肿瘤的化疗和靶向治疗。