医生擅长:
擅长头颈部肿瘤放射治疗,特别是鼻咽癌的精确调强放疗和综合治疗。
医生简介:
1962年10月出生,湖南衡阳人,主任医师,硕士生导师。擅长头颈部肿瘤放射治疗,特别是鼻咽癌的精确调强放疗和综合治疗。曾主持和参与广东省科技计划项目、国家自然科学基金重点项目、卫生部临床学科重点项目多个,参与项目的研究成果荣获2014年广东省科学技术一等奖、中华医学科技一等奖及国家科技进步二等奖。担任Br J Cancer、Cancer Epidemiol Biomarkers Pre、Tumor Biol、Radiat Oncol、Oral Oncol等杂志审稿人。主要研究鼻咽癌综合治疗方案、肿瘤分期及预后因素,近五年以第一作者或通讯作者在Ann Oncol、Br J Cancer、Cancer Epidemiol Biomarkers Pre、J Biol Chem等肿瘤学期刊发表论文15篇,其临床研究成果得到美国癌症研究协会(AACR)网站新闻报道。
荣誉成就:
参与研究项目获2014年广东省科学技术一等奖、中华医学科技一等奖及国家科技进步二等奖。
论文发表:
近五年主要发表论文, 通讯作者(*)或第一作者(?):
1)OuYang PY, Xie C, …, Xie FY *. Significant efficacies of neoadjuvant and adjuvant chemotherapy for nasopharyngeal carcinoma by meta-analysis of published literature-based randomized, controlled trials. Ann Oncol 2013; 24: 2136-2146.
2)OuYang PY, Zhang LN, …, Xie FY *. The significant survival advantage of female sex in nasopharyngeal carcinoma: a propensity-matched analysis. Br J Cancer 2015; 112: 1554-1561.
3)OuYang PY, Su Z, …, Xie FY *. Prognostic impact of family history in southern Chinese patients with undifferentiated nasopharyngeal carcinoma. Br J Cancer 2013; 109: 788-794.
4)OuYang PY, Su Z, …, Xie FY *. Prognostic value of ABO blood group in southern Chinese patients with established nasopharyngeal carcinoma. Br J Cancer 2013; 109: 2462-2466.
5)OuYang PY, Su Z, …, Xie FY *. Comparison of TNM staging systems for nasopharyngeal carcinoma, and proposal of a new staging system. Br J Cancer 2013; 109: 2987-2997.
6)OuYang PY, Su Z, …, Xie FY *. Prognostic impact of cigarette smoking on the survival of patients with established nasopharyngeal carcinoma. Cancer Epidemiol Biomarkers Prev 2013; 22: 2285-2294.
7)Su Z, Mao YP, …, Xie FY *. Leucopenia and treatment efficacy in advanced nasopharyngeal carcinoma. BMC Cancer. 2015; 15: 429.
8)Liang XX, Li Q, …, Xie FY *. Significant Prognostic Impact of Chemoradiotherapy-Induced Hemoglobin Decrease on Treatment Outcomes of Nasopharyngeal Carcinoma. J Cancer 2015; 6: 502-510.
9)Liang X, Shi D, …, Xie FY *. Friend leukemia virus integration 1 expression has prognostic significance in nasopharyngeal carcinoma. Transl Oncol 2014; 7: 493-502.
10)OuYang PY, Su Z, …, Xie FY *. Diabetes, Prediabetes and the Survival of Nasopharyngeal Carcinoma: A Study of 5,860 Patients. PLoS One 2014; 9: e111073.
11)OuYang PY, Su Z, …, Xie FY *. Combination of EGFR-TKIs and Chemotherapy as First-Line Therapy for Advanced NSCLC: A Meta-Analysis. PLoS One 2013; 8: e79000.
12)Wang X, Liang Y, …, Xie FY *. Prognostic significance of SOX2 expression in nasopharyngeal carcinoma. Cancer Invest 2012; 30: 79-85.
13)Xu HM, Liang Y, …, Xie FY *, Kang TB. Correlation of Skp2 overexpression to prognosis of patients with nasopharyngeal carcinoma from South China. Chin J Cancer 2011; 30: 204-212.
14)Wan XB, Jiang R, Xie FY ?, …, Chen MY. Endoscope-guided interstitial intensity-modulated brachytherapy and intracavitary brachytherapy as boost radiation for primary early T stage nasopharyngeal carcinoma. PLoS One 2014; 9: e90048.
15)Lv XB, Xie FY ?, …, Kang T. Damaged DNA-binding protein 1 (DDB1) interacts with Cdh1 and modulates the function of APC/CCdh1. J Biol Chem 2010; 285: 18234-18240.
科研项目:
主要科研项目:
1)中山大学临床医学研究5010计划项目,调强放疗加或不加同期化疗治疗低危鼻咽癌的III期非劣效性、随机对照、多中心研究,经费200万,2015-2025,第一负责人;
2)国家自然科学基金重点项目,cdh1(FZR1)磷酸化新点被调控的机理,对功能的影响及其 意义,经费174万,2009-2013,第二负责人;
3)中山大学临床医学研究5010计划,局部区域晚期鼻咽癌吉西他滨及顺铂诱导化疗联合同期放化疗对比同期放化疗的前瞻性多中心III期临床研究,经费200万, 2014-2023,第三负责人;
4)卫生部临床学科重点项目,基于调强放射疗的鼻咽癌预后模型及TPF诱导化疗的前瞻性研究,经费200万,2010-2013,第三负责人。