医生擅长:
白血病、淋巴瘤、多发性骨髓瘤等恶性血液病的诊断和治疗,异基因造血干细胞移植治疗恶性血液病等。
医生简介:
主任医师、博士生导师,1995年毕业于原浙江医科大学医学系,获医学学士学位。2000年毕业于浙江大学医学院内科血液学,获医学博士学位。2003年11月-2004年11月,德国基尔大学医院从事访问学者研究工作。2005年4月起担任浙江大学内科血液学硕士生导师。2017年7月起内科血液学博士生导师。浙江省医师协会血液科医师分会委员,浙江省免疫学会血液免疫分会委员,浙江省抗癌协会肿瘤靶向及细胞治疗分会委员。主持国家自然科学基金项目1项,国家教育部,省科技厅,省卫生厅科研项目等7项。以第一作者和通讯作者发表SCI论文20篇及国家一级刊物9篇。参与完成课题获得国家科技进步二等奖1项,浙江省科技进步一、二奖5项。目前从事内科学(血液病专业)的临床医疗,教学和科研工作。掌握内科血液病和造血干细胞移植的诊断和治疗技术,尤其在白血病和淋巴瘤等恶性血液病诊治方面有独到的见解,能解决疑难和危重病人的诊疗技术。在血液科疾病的诊断及治疗上积累较丰富经验。熟悉并掌握本专业最新发展及技术。
荣誉成就:
主要论文1.236例慢性粒细胞白血病患者细胞遗传学特性观察。中华血液学杂志,2000,21(1)2.慢性粒细胞白血病60例临床分析。中国现代医学杂志,2000,10(9)3.急性髓系白血病细胞端粒酶活性与疗效关系的初步研究。中华血液学杂志,2001,22(2)4.端粒酶RNA的反义寡核苷酸诱导白血病细胞凋亡的研究。中华血液学杂志,2001,22(5)5.高三尖杉酯碱抑制K562细胞端粒酶活性的实验研究。实用肿瘤杂志,2001,16(4)6.高三尖杉酯碱对HL-60细胞端粒酶的抑制效应。中国药理学与毒理学杂志,2002,16(1)7.Activation of the coagulation system in cancerogenesis and metastasation. Biomedicine & Pharmacotherapy. 2005, 59(3)8.Homoharringtonine-induced apoptosis of human leukemia HL-60 cells is associated with down-regulation of telomerase. American Journal of Chinese Medicine. 2006,34 (2)9.Diffuse large B-cell lymphoma with concurrent gastric adenocarcinoma: case report and literature review.J Int Med Res.2011, 39(5)10.Cutaneous blastic plasmacytoid dendritic cell neoplasm occurring after spontaneous remission of acute myeloid leukemia: a case report and review of literature. Med Oncol.2012, 29(4)11.Clinical analysis and prognostic significance of lymphoma-associated hemophagocytosis in peripheral T cell lymphoma. Ann Hematol.2013, 92(4)12.Prognostic values of various clinical factors and genetic subtypes for diffuse large B-cell lymphoma patients: a retrospective analysis of 227 cases. Asian Pacific J Cancer Prev. 2013, 14(2)13.Clinical analysis and prognostic significance of hepatitis B virus infections for diffuse large B-cell lymphoma with or without rituximab therapy. Experimental and Therapeutic Therapy,2013, 6(1)14.Significance of clinical factors as prognostic indicators for peripheral T-cell non-Hodgkin lymphoma patients: a retrospective analysis of 252 Chinese cases. Molecular and Clinical Oncology. 2013, 1(5)15.An aggressive form of non-Hodgkin’s lymphoma together with pleural and abdominal chylous effusions: a case report and review of the literature. Oncology letters. 2013, 6(4)16.Clinical analysis and prognostic significance of L-asparaginase containing multidrug chemotherapy regimen in incipient peripheral T-cell lymphoma. Int J Clin Exp Med. 2015,8(6)17.外周血造血干细胞动员采集对166 名健康供者血细胞计数的近期影响. 中华血液学杂志. 201518.Clinical observation on hemogram variation of allogeneic donors from Chinese population for peripheral hematopoietic stem cells collection. Stem Cells Dev.2016,25(10)19.外周T细胞淋巴瘤药物治疗的研究进展. 国际输血及血液学杂志. 2016, 39(2)20.Expression and functions of the STAT3-SCLIP pathway in chronic myeloid leukemia cells. Exp Ther Med.2016,12(5)21.Pulmonary leucostasis and trisomy 12 in a young patient with chronic lymphocytic leukemia: a case report and review of literature. Int J Clin Exp Med. 2016,9(11)22.黏膜相关淋巴组织淋巴瘤的发病机制及治疗策略. 国际输血及血液学杂志, 2017, 40(3)23.Clinical features and outcomes in secondary adult hemophagocytic lymphohistiocytosis.QJM. 2018,111(1)24.超敏C 反应蛋白水平对外周T 细胞淋巴瘤患者预后意义的临床研究.中国肿瘤临床,2017,44((17)25.Risk factors of early death in adult patients with secondary hemophagocytic lymphohistiocytosis: a single-institution study of 171 Chinese patients.Hematology. 2019,24(1)26.Body mass index at diagnosis is associated with survival outcome in peripheral T-cell lymphoma: a study of Chinese population.Jpn J Clin Oncol. 2020,50(2)27.The prognostic value of platelet-lymphocyte ratio and neutrophil-lymphocyte ratio in the treatment response and survival of patients with peripheral T-celllymphoma.Leuk Lymphoma. 2020,61(3)28.m6A-binding proteins: the emerging crucial performers in epigenetics.J Hematol Oncol. 2020,13(1)
论文发表:
1. 236例慢性粒细胞白血病患者细胞遗传学特性观察。中华血液学杂志,2000,21(1)
2. 慢性粒细胞白血病60例临床分析。中国现代医学杂志,2000,10(9)
3. 急性髓系白血病细胞端粒酶活性与疗效关系的初步研究。中华血液学杂志,2001,22(2)
4. 端粒酶RNA的反义寡核苷酸诱导白血病细胞凋亡的研究。中华血液学杂志,2001,22(5)
社会任职:
浙江大学医学院附属第一医院血液科副主任
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非常耐心,临床经验丰富,医术高明,富于同情性。
评价医生: 谢万灼 2008-04-14