北京大学肿瘤医院

医生擅长： 恶性肿瘤的生物免疫治疗，尤其在恶性黑色素瘤和肾癌等多种实体瘤的生物免疫治疗方面有较独特的研究并积累了较丰富的临床经验。

医生简介： 郭军：医学博士、教授、主任医师、博士生导师。现任北京肿瘤医院、北京大学临床肿瘤学院副院长，北京市肿瘤防治研究所副所长，肾癌黑色素瘤内科主任。中国临床肿瘤协会（CSCO）执委会委员，中国临床肿瘤协会（CSCO）黑色素瘤专家委员会主任委员，中国临床肿瘤协会（CSCO）肾癌专家委员会主任委员，国际黑色素瘤研究联盟（Society for Melanoma Research）亚太地区主席，国际黑色素瘤基金会（MIF）海外咨询顾问。中国抗癌协会泌尿肿瘤分会常务委员，«NCCN肾癌诊治指南中国版»执笔人，«中国黑色素瘤诊治共识»及«中国黑色素瘤诊治指南»编写组执笔人。入选教育部 “新世纪优秀人才支持计划”，北京市“十百千”卫生优秀人才，新世纪百千万人才工程北京市级人选。近5年内发表的代表性论著（影响因子61.64分）1. Guo Jun, Si L, Kong Y, Flaherty KT, Xu X, Zhu Y, Corless CL, Li L, Li H, Sheng X, Cui C, Chi Z, Li S, Han M, Mao L, Lin X, Du N, Zhang X, Li J, Wang B, Qin S. A Phase II, Open Label, Single-arm Trial of Imatinib Mesylate in Patients with Metastatic Melanoma Harboring c-Kit Mutation or Amplification. J Clin Oncol. 2011, June 20, 10.1200/JCO.2010.33.9275. (IF=18.96)2. Mao L, Si L, Chi Z, Cui C, Sheng X, Li S, Tang B, Guo Jun. A randomized phase II trial of 1 month versus 1 year of adjuvant high-dose interferon alfa-2b in high-risk acral melanoma patients. Eur J Cancer. 2011(47):1498-1503. (IF=4.943)3. Chi Z, Li S, Sheng X, Si L, Cui C, Han M, Guo Jun. Clinical presentation, histology, and prognoses of malignant melanoma in ethnic Chinese: A study of 522 consecutive cases. BMC Cancer. 2011;11:85. (IF=3.153)4. Kong Y, Si L, Zhu Y, Xu XG, Corless CL, Flaherty K, Li L, Li H, Sheng X, Cui C, Chi Z, Li S, Han M, Mao L, Lu A, Guo Jun. Large Scale Analysis of KIT Aberrations in Chinese Patients with Melanoma. Clin Cancer Res. 2011;17(7): 1684-1691. (IF=7.337)5.Si L, Kong Y, Xu X, Corless CL, Flaherty KT, Sheng X, Cui C, Chi Z, Zhu Y, Li S, Han M, Mao L, Guo Jun. Prevalence of BRAF V600E mutation in Chinese melanoma patients: large scale analysis of BRAF and NRAS mutations in a 432-case cohort. Eur J Cancer.2011. (in press) (IF=4.943)6. Chen T, Guo Jun, Yang M, Zhu X, Cao X. Chemokine-containing exosomes are released from heat-stressed tumor cells via lipid raft-dependent pathway and act as efficient tumor vaccine. J Immunol. 2011;186:2219-28. (共同第一作者，IF=5.745)7. Chen T, Guo Jun, Han C, Yang M, Cao X. Heat shock protein 70, released from heat-stressed tumor cells, initiates antitumor immunity by inducing tumor cell chemokine production and activating dendritic cells via TLR4 pathway. J Immunol. 2009;182:1449-59. (共同第一作者，IF=5.745)8. Schadendorf D, Algarra SM, Bastholt L, Cinat G, Dreno B, Eggermont AM, Espinosa E, Guo J, Hauschild A, Petrella T, Schachter J, Hersey P. Immunotherapy of distant metastatic disease. Ann Oncol. 2009 Aug; 20 Suppl 6:vi41-50. (IF=5.647)9. Lu Si, Zhi-hong Chi, Xiang-qing Yuan, Chuan-liang Cui, Xi-nan Sheng, Guo Jun. A phase II study of fotemustine plus dacarbazine with dendritic cell vaccines as first-line therapy for Chinese patients with advanced acral lentiginous melanoma. Chinese Journal of Cancer Research，2009 Mar 21(1), 13-19. (IF=0.252)10. Guo Jun, Zhu J, Sheng X, Wang X, Qu L, Han Y, Liu Y, Zhang H, Huo L, Zhang S, Lin B, Yang Z. Intratumoral injection of dendritic cells in combination with local hyperthermia induces systemic antitumor effect in patients with advanced melanoma. Int J Cancer. 2007;120:2418-25. (IF=4.926)

荣誉成就： 曾获国家专利一项、省级科技进步二等奖二项、军队科技进步三等奖2项、四等奖一项。国家教育部 “新世纪优秀人才支持计划”入选者，北京市“十百千”卫生优秀人才基金获得者，新世纪百千万人才工程北京市级人选。

论文发表： 在国际著名医学杂志上（Blood, Gene Ther, Int J Cancer等）发表论著4篇，在国内核心期刊发表论著20余篇。

社会任职： 国际黑色素瘤研究联盟（Society forMelanoma Research）常务委员，国际黑色素瘤监督委员会候补委员，全球黑色素瘤专家委员会GMTF（Golbal Melanoma Task Force）委员，黑色素瘤国际基金会（MIF）海外咨询顾问。中国晚期肾癌治疗专家委员会成员。